Space–time clustering patterns in childhood leukaemia support a role for infection

@article{Birch2000SpacetimeCP,
  title={Space–time clustering patterns in childhood leukaemia support a role for infection},
  author={Jillian M. Birch and Freda E. Alexander and Val Blair and O. B. Eden and Graham Malcolm Taylor and Richard James. Mcnally},
  journal={British Journal of Cancer},
  year={2000},
  volume={82},
  pages={1571 - 1576}
}
Previous studies of space–time clustering in childhood leukaemia have produced equivocal and inconsistent results. To address this issue we have used Manchester Children’s Tumour Registry leukaemia data in space–time clustering analyses. Knox tests for space–time interactions between cases were applied with fixed thresholds of close in space, < 5 km and close in time < 1 year apart. Addresses at birth as well as diagnosis were utilized. Tests were repeated replacing geographical distance with… CONTINUE READING
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