Sp1-driven up-regulation of miR-19a decreases RHOB and promotes pancreatic cancer

Abstract

Cancer treatment alters microRNA (miRNA) expression, revealing potential therapeutic targets (oncotarget). Here we treated pancreatic cancer (ASPC-1) cells with either recombinant human endostatin (rh-endostatin) or gemcitabine. Then high-throughput sequencing assay was performed to screen for altered miRNAs. Both treatments decreased levels of MiR-19a. We… (More)

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Cite this paper

@inproceedings{Tan2015Sp1drivenUO, title={Sp1-driven up-regulation of miR-19a decreases RHOB and promotes pancreatic cancer}, author={Yonggang Tan and Hongzhuan Yin and Heying Zhang and Jun Fang and Wei Zheng and Dan Li and Yue Li and Wei Cao and Cheng Sun and Yusi Liang and Juan Zeng and Huawei Zou and Weineng Fu and Xianghong Yang}, booktitle={Oncotarget}, year={2015} }