Soybean transcription factor GmMYBZ2 represses catharanthine biosynthesis in hairy roots of Catharanthus roseus

@article{Zhou2011SoybeanTF,
  title={Soybean transcription factor GmMYBZ2 represses catharanthine biosynthesis in hairy roots of Catharanthus roseus},
  author={Meiliang Zhou and Hong-Li Hou and Xue-mei Zhu and Ji-rong Shao and Yan Wu and Yi-Xiong Tang},
  journal={Applied Microbiology and Biotechnology},
  year={2011},
  volume={91},
  pages={1095-1105}
}
Catharanthus roseus (L.) G. Don is a plant species known for its production of a variety of terpenoid indole alkaloids, many of which have pharmacological activities. Production of catharanthine in cell cultures or in hairy roots established by transformation with Agrobacterium rhizogenes is of interest because catharanthine can be chemically coupled to the abundant leaf alkaloid vindoline to form the valuable anticancer drug vinblastine. Here, we observed a high amount of catharanthine in… CONTINUE READING

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