Soybean β-Conglycinin Induces Inflammation and Oxidation and Causes Dysfunction of Intestinal Digestion and Absorption in Fish

@article{Zhang2013SoybeanI,
  title={Soybean β-Conglycinin Induces Inflammation and Oxidation and Causes Dysfunction of Intestinal Digestion and Absorption in Fish},
  author={J. Zhang and L. Guo and L. Feng and W. Jiang and S. Kuang and Y. Liu and Kai Hu and J. Jiang and S. Li and L. Tang and X. Zhou},
  journal={PLoS ONE},
  year={2013},
  volume={8}
}
β-conglycinin has been identified as one of the major feed allergens. However, studies of β-conglycinin on fish are scarce. This study investigated the effects of β-conglycinin on the growth, digestive and absorptive ability, inflammatory response, oxidative status and gene expression of juvenile Jian carp (Cyprinus carpio var. Jian) in vivo and their enterocytes in vitro. The results indicated that the specific growth rate (SGR), feed intake, and feed efficiency were reduced by β-conglycinin… Expand
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The dynamic process of dietary soybean β-conglycinin in digestion, absorption, and metabolism among different intestinal segments in grass carp (Ctenopharyngodon idella)
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Dietary soya allergen β‐conglycinin induces intestinal inflammatory reactions, serum‐specific antibody response and growth reduction in a carnivorous fish species, turbot Scophthalmus maximus L.
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Soybean β-conglycinin caused intestinal inflammation and oxidative damage in association with NF-κB, TOR and Nrf2 in juvenile grass carp (Ctenopharyngodon idella): Varying among different intestinal segments.
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Dietary soybean β‐conglycinin suppresses growth performance and inconsistently triggers apoptosis in the intestine of juvenile grass carp (Ctenopharyngodon idella) in association with ROS‐mediated MAPK signalling
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Improvement of dietary N-acetylcysteine on growth inhibition and intestinal damage induced by β-conglycinin in juvenile Chinese mitten crabs (Eriocheir sinensis)
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Soyabean glycinin depresses intestinal growth and function in juvenile Jian carp (Cyprinus carpio var Jian): protective effects of glutamine.
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Effect of dietary isoleucine on the immunity, antioxidant status, tight junctions and microflora in the intestine of juvenile Jian carp (Cyprinus carpio var. Jian).
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N-Acetylcysteine improves intestinal function and attenuates intestinal autophagy in piglets challenged with β-conglycinin
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Dietary gossypol reduced intestinal immunity and aggravated inflammation in on‐growing grass carp (Ctenopharyngodon idella)
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