SoxRS down-regulation of rob transcription.

  title={SoxRS down-regulation of rob transcription.},
  author={Carmen Mich{\'a}n and Manuel Manchado and Carmen Pueyo},
  journal={Journal of bacteriology},
  volume={184 17},
Rob is regarded as a constitutively expressed protein, although little is known about how rob gene is regulated. We show here by reverse transcription-PCR that the transcriptional levels of rob are strongly down-regulated in response to the superoxide-generating agent paraquat (PQ). Repression reached a maximum of 20-fold after 10 min exposure at 10 microM PQ. The magnitude of rob repression was comparable to that of induction quantified for the most sensitive SoxS targets. beta-Galactosidase… CONTINUE READING
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