SoxE factors function equivalently during neural crest and inner ear development and their activity is regulated by SUMOylation.

@article{Taylor2005SoxEFF,
  title={SoxE factors function equivalently during neural crest and inner ear development and their activity is regulated by SUMOylation.},
  author={Kimberly M Taylor and Carole LaBonne},
  journal={Developmental cell},
  year={2005},
  volume={9 5},
  pages={593-603}
}
Sox9 and the closely related factor Sox10 are essential for the formation of neural crest precursor cells, and play divergent roles in the process by which these cells are subsequently directed to form specific derivatives. These group E Sox factors have also been implicated in the development of the vertebrate inner ear. Despite their importance, however, the mechanisms that allow SoxE proteins to regulate such a diverse range of cell types have remained poorly understood. Here we demonstrate… CONTINUE READING

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