Sox10 overexpression induces neural crest-like cells from all dorsoventral levels of the neural tube but inhibits differentiation.

@article{Mckeown2005Sox10OI,
  title={Sox10 overexpression induces neural crest-like cells from all dorsoventral levels of the neural tube but inhibits differentiation.},
  author={S Mckeown and Vivian M. Lee and Marianne Bronner-Fraser and Donald F. Newgreen and Peter G Farlie},
  journal={Developmental dynamics : an official publication of the American Association of Anatomists},
  year={2005},
  volume={233 2},
  pages={430-44}
}
SoxE genes (Sox8, Sox9, and Sox10) are early response genes to neural crest induction. Although the early role of Sox9 has been examined in chick and frog, later roles in neural crest migration and differentiation remain largely unexplored. We first examined which SoxE genes were expressed in trunk neural crest cells and then investigated their function using in ovo electroporation. The results of this analysis reveal that Sox10 is present in migrating neural crest cells, whereas other SoxE… CONTINUE READING