Southern African ancient genomes estimate modern human divergence to 350,000 to 260,000 years ago
@article{Schlebusch2017SouthernAA, title={Southern African ancient genomes estimate modern human divergence to 350,000 to 260,000 years ago}, author={Carina M. Schlebusch and Helena Malmstr{\"o}m and Torsten G{\"u}nther and Per Sj{\"o}din and Alexandra Coutinho and Hanna Edlund and Arielle R. Munters and M{\'a}rio Vicente and Maryna Steyn and Himla Soodyall and Marlize Lombard and Mattias Jakobsson}, journal={Science}, year={2017}, volume={358}, pages={652 - 655} }
Ancient DNA pushes human emergence back Anatomically modern humans evolved in Africa, but pinpointing when has been difficult. Schlebusch et al. sequenced three ancient African genomes from the Stone Age, about 2000 years old, and four from the Iron Age, 300 to 500 years old. One of the oldest samples, sequenced to 13× coverage, appears most closely to resemble individuals from the present-day San population. However, this individual seems to have lacked genetic contributions from other modern…
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References
SHOWING 1-10 OF 113 REFERENCES
Ancient Ethiopian genome reveals extensive Eurasian admixture in Eastern Africa
- BiologyScience
- 2015
The genome of an Ethiopian male, “Mota,” who lived approximately 4500 years ago is sequenced to demonstrate that the Eurasian backflow into Africa came from a population closely related to Early Neolithic farmers, who had colonized Europe 4000 years earlier.
The genetic history of Ice Age Europe
- BiologyNature
- 2016
Modern humans arrived in Europe ~45,000 years ago, but little is known about their genetic composition before the start of farming ~8,500 years ago. We analyze genome-wide data from 51 Eurasians from…
Ancient Genomics and the Peopling of the Southwest Pacific
- Environmental ScienceNature
- 2016
The finding that the ancient individuals had little to no Papuan ancestry implies that later human population movements spread Papuan Ancestry through the South Pacific after the first peopling of the islands.
African populations and the evolution of human mitochondrial DNA.
- BiologyScience
- 1991
The African origin hypothesis of human mtDNA evolution is supported by two statistical tests and two hypervariable segments of mtDNA were sequenced from 189 people of diverse geographic origin, including 121 native Africans.
First Ancient Mitochondrial Human Genome from a Prepastoralist Southern African
- BiologyGenome biology and evolution
- 2014
Providing the first genomic evidence that prepastoral Southern African marine foragers carried the earliest diverged maternal modern human lineages, this study emphasizes the significance of Southern African archeological remains in defining early modern human origins.
Inferring human population size and separation history from multiple genome sequences
- BiologyNature Genetics
- 2014
Results from applying multiple sequentially Markovian coalescent (MSMC) to genome sequences from nine populations across the world suggest that the genetic separation of non-African ancestors from African Yoruban ancestors started long before 50,000 years ago and give information about human population history as recent as 2,000 Years ago.
The genetic prehistory of southern Africa
- BiologyNature communications
- 2012
It is found that all individuals derive at least a few percent of their genomes from admixture with non-Khoisan populations that began ∼1,200 years ago, supporting the hypothesis of an ancient link between southern and eastern Africa.
Bayesian inference of ancient human demography from individual genome sequences
- BiologyNature Genetics
- 2011
This work used a Bayesian, coalescent-based approach to obtain information about ancestral population sizes, divergence times and migration rates from inferred genealogies at many neutrally evolving loci across the genome.
Genomic Variation in Seven Khoe-San Groups Reveals Adaptation and Complex African History
- BiologyScience
- 2012
Genetic variation in various sub-Saharan populations did not localize the origin of modern humans to a single geographic region within Africa; instead, it indicated a history of admixture and stratification, and illustrated the importance of African genomic diversity in understanding human evolutionary history.
The making of the African mtDNA landscape.
- BiologyAmerican journal of human genetics
- 2002
The results suggest that the southeast Bantu speakers have a composite origin on the maternal line of descent, with approximately 44% of lineages deriving from West Africa, approximately 21% from either West or Central Africa, Approximately 30% from East Africa, and approximately 5% from southern African Khoisan-speaking groups.