South African guideline for the management of chronic hepatitis B: 2013.

@article{Spearman2013SouthAG,
  title={South African guideline for the management of chronic hepatitis B: 2013.},
  author={Catherine Wendy Spearman and Mark Wayne Sonderup and Jean Frederick Botha and Schalk Willem van der Merwe and Ernest Koh Wee Song and Chris Kassianides and Kelly Ann Newton and Henry Norman Hairwadzi},
  journal={South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde},
  year={2013},
  volume={103 5 Pt 2},
  pages={
          337-49
        }
}
Hepatitis B remains a significant yet preventable health issue in South Africa. The introduction of the hepatitis B vaccine into the country some 18 years ago has demonstrated benefit, but the exposure to, and prevalence of chronic HBsAg positivity remain unacceptably high. Those with chronic hepatitis B virus infection have an elevated risk of developing cirrhosis with end-stage liver disease and a markedly elevated risk of hepatocellular carcinoma, independent of the presence of cirrhosis… CONTINUE READING

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