Sources of calcium in neurokinin A–induced contractions of human colonic smooth muscle in vitro

Abstract

OBJECTIVES:Tachykinins have been implicated in the pathogenesis of colonic dysmotility. The sources of activator calcium for neurokinin A (NKA)–induced contraction of human colonic smooth muscle have not been assessed. We evaluated the contribution of extracellular and intracellular Ca2+ to NKA-induced contractions.METHODS:Circular smooth muscle strips of… (More)
DOI: 10.1111/j.1572-0241.2001.05257.x

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