Source and regulation of flux variability in Escherichia coli

  title={Source and regulation of flux variability in Escherichia coli},
  author={Magdalena San Rom{\'a}n and H{\'e}ctor Cancela and Luis Acerenza},
  booktitle={BMC Systems Biology},
Metabolic responses are essential for the adaptation of microorganisms to changing environmental conditions. The repertoire of flux responses that the metabolic network can display in different external conditions may be quantified applying flux variability analysis to genome-scale metabolic reconstructions. A procedure is developed to classify and quantify the sources of flux variability. We apply the procedure to the latest Escherichia coli metabolic reconstruction, in glucose minimal medium… CONTINUE READING
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