Sorting out Sox10 functions in neural crest development.

@article{Kelsh2006SortingOS,
  title={Sorting out Sox10 functions in neural crest development.},
  author={Robert N Kelsh},
  journal={BioEssays : news and reviews in molecular, cellular and developmental biology},
  year={2006},
  volume={28 8},
  pages={
          788-98
        }
}
For both vertebrate developmental and evolutionary biologists, and also for clinicians, the neural crest (NC) is a fundamental cell population. An understanding of Sox10 function in NC development is of particular significance since Sox10 mutations underlie several neurocristopathies. Surprisingly, experiments in different model organisms aimed at identifying Sox10's role(s) have suggested at least four distinct functions. Sox10 may be critical for formation of neural crest cells (NCCs… CONTINUE READING
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