Sorting of peroxisomal membrane protein PMP47 from Candida boidinii into peroxisomal membranes of Saccharomyces cerevisiae.

@article{McCammon1990SortingOP,
  title={Sorting of peroxisomal membrane protein PMP47 from Candida boidinii into peroxisomal membranes of Saccharomyces cerevisiae.},
  author={Mark T. McCammon and C A Dowds and Kim Orth and Carolyn R. Moomaw and Clive A. Slaughter and Joel M Goodman},
  journal={The Journal of biological chemistry},
  year={1990},
  volume={265 33},
  pages={20098-105}
}
A gene encoding PMP47, a peroxisomal integral membrane protein of the methylotrophic yeast Candida boidinii, was isolated from a genomic library. DNA sequencing of PMP47 revealed an open reading frame of 1269 base pairs capable of encoding a protein of 46,873 Da. At least two membrane-spanning regions in the protein are predicted from the sequence. Since the 3 amino acids at the carboxyl terminus are -AKE, PMP47 lacks a typical peroxisomal sorting signal. No significant similarities in primary… CONTINUE READING