Sorting nexins--unifying trends and new perspectives.

  title={Sorting nexins--unifying trends and new perspectives.},
  author={Jez G. Carlton and Miriam V. Bujny and Anna C. Rutherford and Pete J Cullen},
  volume={6 2},
The sorting nexins (SNXs) are a family of PX domain-containing proteins found in yeast and mammalian cells that have been proposed to regulate intracellular trafficking. Mammalian SNXs have been suggested to function variously in pro-degradative sorting, internalization, endosomal recycling, or simply in endosomal sorting. In yeast, the defining function for these proteins is a regulation of cargo retrieval. Here we examine recent data on the SNX family of proteins and attempt to draw out… CONTINUE READING

From This Paper

Topics from this paper.


Publications citing this paper.
Showing 1-10 of 82 extracted citations

Similar Papers

Loading similar papers…