Sorting nexins--unifying trends and new perspectives.

@article{Carlton2005SortingNT,
  title={Sorting nexins--unifying trends and new perspectives.},
  author={Jez G. Carlton and Miriam V. Bujny and Anna C. Rutherford and Pete J Cullen},
  journal={Traffic},
  year={2005},
  volume={6 2},
  pages={75-82}
}
The sorting nexins (SNXs) are a family of PX domain-containing proteins found in yeast and mammalian cells that have been proposed to regulate intracellular trafficking. Mammalian SNXs have been suggested to function variously in pro-degradative sorting, internalization, endosomal recycling, or simply in endosomal sorting. In yeast, the defining function for these proteins is a regulation of cargo retrieval. Here we examine recent data on the SNX family of proteins and attempt to draw out… CONTINUE READING

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