Sorbitol synthesis by an engineered Lactobacillus casei strain expressing a sorbitol-6-phosphate dehydrogenase gene within the lactose operon.

@article{Nissen2005SorbitolSB,
  title={Sorbitol synthesis by an engineered Lactobacillus casei strain expressing a sorbitol-6-phosphate dehydrogenase gene within the lactose operon.},
  author={Lorenzo Nissen and Gaspar P{\'e}rez-Mart{\'i}nez and Mar{\'i}a Jes{\'u}s Yebra},
  journal={FEMS microbiology letters},
  year={2005},
  volume={249 1},
  pages={177-83}
}
Sorbitol is claimed to have important health-promoting effects and Lactobacillus casei is a lactic acid bacterium relevant as probiotic and used as a cheese starter culture. A sorbitol-producing L. casei strain might therefore be of considerable interest in the food industry. A recombinant strain of L. casei was constructed by the integration of a d-sorbitol-6-phosphate dehydrogenase-encoding gene (gutF) in the chromosomal lactose operon (strain BL232). gutF expression in this strain followed… CONTINUE READING
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