Sorbitol Pathway: Presence in Nerve and Cord with Substrate Accumulation in Diabetes

  title={Sorbitol Pathway: Presence in Nerve and Cord with Substrate Accumulation in Diabetes},
  author={K. Gabbay and L. Merola and R. A. Field},
  pages={209 - 210}
  • K. Gabbay, L. Merola, R. A. Field
  • Published 1966
  • Medicine
  • Science
  • Glucose, sorbitol, fructose, and inositol are present in peripheral nerve and spinal cord. Marked elevation of these substances occurs in these tissues in mildly diabetic animals. These alterations provide biochemical mechanisms which could be significant in the etiology of diabetic neuropathy. 
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    Kinoshita for his interest and encouragement in this project. Supported in part by PHS grants NB-04063-04 and TI AM 5072