Sorafenib protects human optic nerve head astrocytes from light-induced overexpression of vascular endothelial growth factor, platelet-derived growth factor, and placenta growth factor.

@article{Kernt2010SorafenibPH,
  title={Sorafenib protects human optic nerve head astrocytes from light-induced overexpression of vascular endothelial growth factor, platelet-derived growth factor, and placenta growth factor.},
  author={Marcus Kernt and Raffael G Liegl and Johann Rueping and Aljoscha Steffen Neubauer and Christos Haritoglou and C A Lackerbauer and Kirsten H Eibl and Michael Werner Ulbig and Anselm Kampik},
  journal={Growth factors},
  year={2010},
  volume={28 3},
  pages={211-20}
}
OBJECTIVES Growth factors, such as vascular endothelial growth factor (VEGF), platelet-derived growth factor (PDGF), and placenta growth factor (PlGF) are key players in the development of diabetic retinopathy, age-related macular degeneration, and other retinal neovascular diseases. Glial cells provide a significant source of retinal growth factor production under physiologic and pathologic conditions. Cumulative light exposure has been linked to increased retinal growth factor expression… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-9 of 9 extracted citations

Similar Papers

Loading similar papers…