Sonoporation by low-frequency and low-power ultrasound enhances chemotherapeutic efficacy in prostate cancer cells in vitro

@inproceedings{Wang2013SonoporationBL,
  title={Sonoporation by low-frequency and low-power ultrasound enhances chemotherapeutic efficacy in prostate cancer cells in vitro},
  author={Yu Wang and Wen-kun Bai and E Shen and Bing Hu},
  booktitle={Oncology letters},
  year={2013}
}
Combination therapy is used to optimize anticancer efficacy and reduce the toxicity and side-effects of drugs upon systemic administration. Ultrasound (US) combined with micro-bubbles (UM) enhances the intracellular uptake of cytotoxic drugs by tumor cells, particularly drug-resistant cells. In the present study, low-frequency and low-energy US (US irradiation conditions: frequency, 21 kHz; power density, 0.113 W/cm2; exposure time, 2 min at a duty cycle of 70%; and valid treatment time, 84 sec… CONTINUE READING

References

Publications referenced by this paper.
Showing 1-10 of 22 references

The improvement of liposome ‐ mediated transfection of pEGFP DNA into human prostate cancer cells by combining low ‐ frequency and low ‐ energy ultrasound with microbubbles

  • Q Hao, Q Liu, X Wang, P Wang, T Li, WY Tong
  • Oncol Rep
  • 2012

: the impact of eliminating socioeconomic and racial disparities on premature cancer deaths

  • J Carles, D Castellano, MÁ Climent, P Maroto, R Medina, A Alcaraz
  • CA Cancer J Clin
  • 2011

Cancer statistics ,

  • R Siegel, E Ward, O Brawley, A Jemal
  • 2011

Design and evaluation of doxorubicin ‐ containing microbubbles for ultrasound ‐ triggered doxorubicin delivery : cytotoxicity and mechanisms involved

  • S Sonoda, K Tachibana, E Uchino
  • Mol Ther
  • 2010

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