Sonoporation-Enhanced Chemotherapy Significantly Reduces Primary Tumour Burden in an Orthotopic Pancreatic Cancer Xenograft

@article{Kotopoulis2013SonoporationEnhancedCS,
  title={Sonoporation-Enhanced Chemotherapy Significantly Reduces Primary Tumour Burden in an Orthotopic Pancreatic Cancer Xenograft},
  author={Spiros Kotopoulis and Anthony Delalande and Mihaela Octavia Popa and Veronika Mamaeva and Georg Dimcevski and Odd Helge Gilja and Michiel Postema and Bj\orn Tore Gjertsen and Emmet Mccormack},
  journal={Molecular Imaging and Biology},
  year={2013},
  volume={16},
  pages={53-62}
}
Adenocarcinoma of the pancreas remains one of the most lethal human cancers. The high mortality rates associated with this form of cancer are subsequent to late-stage clinical presentation and diagnosis, when surgery is rarely possible and of modest chemotherapeutic impact. Survival rates following diagnosis with advanced pancreatic cancer are very low; typical mortality rates of 50 % are expected within 3 months of diagnosis. However, adjuvant chemotherapy improves the prognosis of patients… CONTINUE READING

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