Sonophoresis Effect on the Permeation of Metronidazole Using 3 D Skin Equivalent

@inproceedings{Aldwaikat2012SonophoresisEO,
  title={Sonophoresis Effect on the Permeation of Metronidazole Using 3 D Skin Equivalent},
  author={Mai Aldwaikat and Mohammed Alarjah and Jacki Willis and Timothy Mason},
  year={2012}
}
Transdermal drug delivery is highly advantageous method for drug administration, yet the compact structure of stratum corneum is an effective barrier which limited the use of this route to very few drug molecules. Ultrasound enhances the permeation through the skin by altering this barrier function in a phenomenon named sonophoresis. This study aimed to evaluate the effect of variable ultrasonic conditions on the permeation of Metronidazole (ML). This involved validating the applicability of… CONTINUE READING