Sonodynamic therapy--a review of the synergistic effects of drugs and ultrasound.

@article{Rosenthal2004SonodynamicTR,
  title={Sonodynamic therapy--a review of the synergistic effects of drugs and ultrasound.},
  author={Ionel Rosenthal and Joe Z. Sostaric and Peter C. Riesz},
  journal={Ultrasonics sonochemistry},
  year={2004},
  volume={11 6},
  pages={
          349-63
        }
}
Sonodynamic therapy, the ultrasound dependent enhancement of cytotoxic activities of certain compounds (sonosensitizers) in studies with cells in vitro and in tumor bearing animals, is reviewed. The attractive features of this modality for cancer treatment emerges from the ability to focus the ultrasound energy on malignancy sites buried deep in tissues and to locally activate a preloaded sonosensitizer. Possible mechanisms of sonodynamic therapy include generation of sonosensitizer derived… CONTINUE READING

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