Sonic hedgehog signaling plays an essential role during embryonic salivary gland epithelial branching morphogenesis.

@article{Jaskoll2004SonicHS,
  title={Sonic hedgehog signaling plays an essential role during embryonic salivary gland epithelial branching morphogenesis.},
  author={Tina Jaskoll and Troy Leo and Daniel Witcher and Mattias Ormestad and J Astorga and Pablo O Bringas and Peter Carlsson and Michael M Melnick},
  journal={Developmental dynamics : an official publication of the American Association of Anatomists},
  year={2004},
  volume={229 4},
  pages={
          722-32
        }
}
Gene targeting studies indicate that sonic hedgehog (Shh) signaling plays an essential role during craniofacial development. Because numerous mandibular derivatives (e.g., teeth, tongue, Meckel's cartilage) are absent in Shh null mice and the embryonic submandibular salivary gland (SMG) develops from the mandibular arch, we postulated that Shh signaling is important for embryonic SMG development. To address this question, we first determined the spatiotemporal distribution of Shh; two… CONTINUE READING
Highly Cited
This paper has 65 citations. REVIEW CITATIONS

Citations

Publications citing this paper.
Showing 1-10 of 62 citations

66 Citations

0510'06'09'12'15'18
Citations per Year
Semantic Scholar estimates that this publication has 66 citations based on the available data.

See our FAQ for additional information.

References

Publications referenced by this paper.
Showing 1-10 of 79 references

TGF-beta1 inhibits growth and branching morphogenesis in embryonic mouse submandibular

  • P Hardman, E Landels, A Woolfe, B. Spooner
  • 1994
Highly Influential
4 Excerpts