Sonic hedgehog lineage in the mouse hypothalamus: from progenitor domains to hypothalamic regions

@inproceedings{AlvarezBolado2011SonicHL,
  title={Sonic hedgehog lineage in the mouse hypothalamus: from progenitor domains to hypothalamic regions},
  author={Gonzalo Alvarez-Bolado and Fabian Alexander Paul and Sandra Blaess},
  booktitle={Neural Development},
  year={2011}
}
The hypothalamus is a brain region with essential functions for homeostasis and energy metabolism, and alterations of its development can contribute to pathological conditions in the adult, like hypertension, diabetes or obesity. However, due to the anatomical complexity of the hypothalamus, its development is not well understood. Sonic hedgehog (Shh) is a key developmental regulator gene expressed in a dynamic pattern in hypothalamic progenitor cells. To obtain insight into hypothalamic… CONTINUE READING
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