Sonic hedgehog elevates N-myc gene expression in neural stem cells★

@inproceedings{Liu2012SonicHE,
  title={Sonic hedgehog elevates N-myc gene expression in neural stem cells★},
  author={Dongsheng Liu and Shouyu Wang and Yan Cui and Lun Shen and Yanping Du and Guilin Li and Bo Zhang and Renzhi Wang},
  booktitle={Neural regeneration research},
  year={2012}
}
Proliferation of neural stem cells is regulated by the secreted signaling molecule sonic hedgehog. In this study, neural stem cells were infected with recombinant adeno-associated virus expressing sonic hedgehog-N-enhanced green fluorescent protein. The results showed that overexpression of sonic hedgehog in neural stem cells induced the increased… CONTINUE READING