Somite subdomains, muscle cell origins, and the four muscle regulatory factor proteins

@article{Smith1994SomiteSM,
  title={Somite subdomains, muscle cell origins, and the four muscle regulatory factor proteins},
  author={Trenton H Smith and Amy M. Kachinsky and John B Miller},
  journal={The Journal of Cell Biology},
  year={1994},
  volume={127},
  pages={95 - 105}
}
We show by immunohistology that distinct expression patterns of the four muscle regulatory factor (MRF) proteins identify subdomains of mouse somites. Myf-5 and MyoD are, at specific stages, each expressed in both myotome and dermatome cells. Myf-5 expression is initially restricted to dorsal cells in all somites, as is MyoD expression in neck somites. In trunk somites, however, MyoD is initially expressed in ventral cells. Myogenin and MRF4 are restricted to myotome cells, though the MRF4… CONTINUE READING

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References

Publications referenced by this paper.
SHOWING 1-10 OF 44 REFERENCES

Myogenic lineages within the developing somite

C. P. Ordahl
  • Molecular Basis of Morphogenesis: 51 st Annual Symposium of the Society for Developmental Biology. M. Bernfield, editor. John Wiley and Sons, New York. 265-276.
  • 1993
VIEW 4 EXCERPTS
HIGHLY INFLUENTIAL

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