Some properties of the thiamine uptake system in isolated rat hepatocytes.

@article{Yoshioka1984SomePO,
  title={Some properties of the thiamine uptake system in isolated rat hepatocytes.},
  author={K. Yoshioka},
  journal={Biochimica et biophysica acta},
  year={1984},
  volume={778 1},
  pages={
          201-9
        }
}
  • K. Yoshioka
  • Published 1984
  • Chemistry, Medicine
  • Biochimica et biophysica acta
A kinetic study of [14C]thiamine uptake over a concentration range from 0.1 microM to 4 mM was performed in isolated rat hepatocytes. The results showed that two processes contribute to the entry in rat hepatocytes: a low affinity process with a Kt of 34.1 microM and Vmax of 20.8 pmol/10(5) cells per 30 s and a high affinity process with a Kt of 1.26 microM and Vmax of 1.21 pmol/10(5) cells per 30 s. The uptake of thiamine by the high affinity process was concentrative and reduced in a betaine… Expand
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