Some properties of acetylcholine receptors in human cultured myotubes.

@article{Adams1985SomePO,
  title={Some properties of acetylcholine receptors in human cultured myotubes.},
  author={David J Adams and Stuart Bevan},
  journal={Proceedings of the Royal Society of London. Series B, Biological sciences},
  year={1985},
  volume={224 1235},
  pages={183-96}
}
The distribution and single channel properties of acetylcholine (ACh) receptors in human myotubes grown in tissue culture have been examined. Radioautography of myotubes labelled with [125I]alpha-bungarotoxin showed that ACh receptors are distributed uniformly over the myotube surface at a density of 3.9 +/- 0.5 receptors per square micrometre. Accumulations of ACh receptors (hot spots) were found rarely. The conductance and kinetics of ACh-activated channels were investigated with the patch… CONTINUE READING