Some pregnancy-related effects of artemether in laboratory animals.

  title={Some pregnancy-related effects of artemether in laboratory animals.},
  author={Janet I. Ejiofor and Helen Ochuko Kwanashie and Joseph A Anuka},
  volume={77 4},
Artemether, highly effective in multi-drug-resistant malaria is not routinely available for use in pregnancy due to the lack of adequate research data in animals and man. This study was therefore aimed at investigating some pregnancy-related effects of artemether. Artemether (1.5, 7.5 and 15 mg/kg i.p. daily for 7 days) did not produce changes in rat oestrous cycle. The drug did not prevent or prolong the rate of conception or parturition, cause pre-term delivery and affect litter size. Birth… CONTINUE READING

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