Some physicochemical properties of FK906: glass transition and relaxation.

@article{Jang1995SomePP,
  title={Some physicochemical properties of FK906: glass transition and relaxation.},
  author={Jin Wook Jang and Shinichi Kitamura and J. Keith Guillory},
  journal={PDA journal of pharmaceutical science and technology},
  year={1995},
  volume={49 1},
  pages={42-9}
}
FK906, a tripeptide antihypertensive agent, was used as a model compound to study some physicochemical properties of peptides and peptide-related compounds. Our results indicate that lyophilization, grinding and melting or storing the samples under conditions of high relative humidity affect chemical stability and crystallinity of FK906. In a preliminary study of lyophilization process design, an extended phase diagram for FK906 in aqueous solution was constructed, and the effects of cooling… CONTINUE READING

From This Paper

Topics from this paper.

Similar Papers

Loading similar papers…