Some lessons from Rickettsia genomics.

@article{Renesto2005SomeLF,
  title={Some lessons from Rickettsia genomics.},
  author={Patricia Renesto and Hiroyuki Ogata and St{\'e}phane Audic and Jean-Michel Claverie and Didier Raoult},
  journal={FEMS microbiology reviews},
  year={2005},
  volume={29 1},
  pages={99-117}
}
Sequencing of the Rickettsia conorii genome and its comparison with its closest sequenced pathogenic relative, i.e., Rickettsia prowazekii, provided powerful insights into the evolution of these microbial pathogens. However, advances in our knowledge of rickettsial diseases are still hindered by the difficulty of working with strict intracellular bacteria and their hosts. Information gained from comparing the genomes of closely related organisms will shed new light on proteins susceptible to be… CONTINUE READING

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