Some enzymatic characteristics of eosinophil peroxidase from patients with eosinophilia and from healthy donors.

@article{Bs1981SomeEC,
  title={Some enzymatic characteristics of eosinophil peroxidase from patients with eosinophilia and from healthy donors.},
  author={Angelo J B{\'o}s and Ron Wever and Mic N. Hamers and Dirk Roos},
  journal={Infection and immunity},
  year={1981},
  volume={32 2},
  pages={427-31}
}
Some enzymatic characteristics of human eosinophil peroxidase were compared with those of human myeloperoxidase. Both enzymes catalyzed the oxidation of iodide by hydrogen peroxide. This assay proved to be very sensitive; the activity of 100 eosinophils/ml could be measured. The position of the pH optimum of this reaction was linearly dependent on the logarithm of the iodide/H2O2 ratio. At the same substrate ratio, this optimum was about 1 pH unit higher for eosinophil peroxidase than for… CONTINUE READING

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