Some effects of metolazone on electrolyte transport.

@article{Odlind1987SomeEO,
  title={Some effects of metolazone on electrolyte transport.},
  author={B. Odlind and B. Beermann and B. Lindstr{\"o}m and O. Eriksson},
  journal={Upsala journal of medical sciences},
  year={1987},
  volume={92 1},
  pages={
          19-35
        }
}
Metolazone action was studied 1) in vitro on isolated operculum of Fundulus heteroclitus (active chloride transport) using an Ussing chamber (metolazone conc 500 microM) and in vivo 2) using the modified Sperber technique in the hen (metolazone infusion rate 0.75-1.2 micrograms/kg/min) and 3) in healthy volunteers using clearance techniques (metolazone infusion rate 10 mg/h). Metolazone reduced (p less than 0.05) short circuit current potential differences with 20% from average control values… Expand

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