Some Structural Aspects of the Peptidyl Transferase Reaction

Abstract

The peptidyl transferase reaction catalyzed by the ribosome has been attracting rapt attention of biochemists for several decades. The ribosome promotes formation of a new peptide bond by transfer of the peptidyl residue (whose C-terminal carbonyl group is activated by ester bonding with the 3' end of the P (donor) site-bound tRNA) to the α -amino group of… (More)
DOI: 10.1023/A:1024247612994

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