Some Parallels Between Gene Control Systems in Maize and in Bacteria

@article{Mcclintock1961SomePB,
  title={Some Parallels Between Gene Control Systems in Maize and in Bacteria},
  author={B. Mcclintock},
  journal={The American Naturalist},
  year={1961},
  volume={95},
  pages={265 - 277}
}
  • B. Mcclintock
  • Published 1 September 1961
  • Biology
  • The American Naturalist
In this article, McClintock attempted to link the regulation of controlling elements to observations made by Francois Jacob, Jacques Monod, and Andre Lwoff on bacterial operons in 1960. In part, McClintock was trying to establish her preeminence in the study of gene regulation, but she also wanted to demonstrate that regulation was widespread among organisms. Many of the parallels she observed were not universally accepted and McClintock backed off most of her claims by 1968. 

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References

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This is McClintock's only research article on controlling units to appear in a peer-reviewed journal and demonstrates that she was able to select a specific gene and make it mutable.

Genetic regulatory mechanisms in the synthesis of proteins.

Genetic and cytological studies of maize

In this report, McClintock described how phase changes could occur at any stage of development and on any part of the plant. By this time, McClintock began to see her system of understanding

The Pale Green Mutable System in Maize.

This report is an analysis of the pale green mutable gene system and its various components, which is similar in many ways to previously described systems and, in addition, there is evidence for an even closer relationship of component parts.

REGULATION BY COLIPHAGE LAMBDA OF THE EXPRESSION OF THE CAPACITY TO SYNTHESIZE A SEQUENCE OF HOST ENZYMES.

Primary human amnion cells cultured under defined conditions were inoculated with a variant of Type II poliovirus and observed for over four months, and the initial cytopathic effect was overcome, and gradually confluent sheets of healthy-appearing cells of altered appearance developed.

The Suppressor-Mutator System of Control of Gene Action in Maize

This manuscript draft reflected McClintock's increasingly complex understanding of the suppressor-mutator as represented in her Carnegie Institution reports after 1956.

Structural and Functional Bases for the Action of the A Alleles in Maize

Analyses of crossover derivatives from certain heterozygotes carrying the Ab "allele" indicate that the separable elements of Ab reside in adjacent members of a duplication. Thus the occurrence, in

Controlling elements and the gene.

  • B. Mcclintock
  • Economics
    Cold Spring Harbor symposia on quantitative biology
  • 1956
This paper presented at the 1956 Cold Spring Harbor Symposium provides a brief overview of McClintock's thoughts on controlling elements, including suppressor-mutator, or Spm.

Paramutation and Chromosome Organization

It is concluded that possibly paramutation may be a very general phenomenon that operates as an information exchanges during differentiation and development of the organism.

Curly Flagellar Mutants in Salmonella

A curly flagellar mutant obtained from a strain of Salmonella typhimurium was unstable and repeatedly dissociated ‘curly’ and normal subclones, suggesting that in each phase the mutant sites of the curly types are very closely linked or identical.