Some Characteristics of an Exceptionally Potent Inhaled Anesthetic: Thiomethoxyflurane

@article{Tanifuji1977SomeCO,
  title={Some Characteristics of an Exceptionally Potent Inhaled Anesthetic: Thiomethoxyflurane},
  author={Yasumasa Tanifuji and Edmond I. Eger and Ross C. Terrell},
  journal={Anesthesia \& Analgesia},
  year={1977},
  volume={56},
  pages={387–390}
}
The authors sought to test whether a deviation existed for the correlation between anesthetic potency and the oil/gas partition coefficient at an extreme of lipid solubility. For thiomethoxyflurane, the sulfur analog of methoxyflurane, the oil/gas partition coefficient was 7230 ± 50 SEM, and MAC (minimum alveolar concentration of thiomethoxyflurane required for anesthesia) in 4 dogs was 0.035 ± 0.008 percent of 1 atm. This agrees with the potency predicted by the lipid solubility, although… Expand
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Anesthetic uptake and action
Find loads of the anesthetic uptake and action book catalogues in this site as the choice of you visiting this page. You can also join to the website book library that will show you numerous booksExpand
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