Somatotopy in the Human Motor Cortex Hand Area. A High‐Resolution Functional MRI Study

@article{Kleinschmidt1997SomatotopyIT,
  title={Somatotopy in the Human Motor Cortex Hand Area. A High‐Resolution Functional MRI Study},
  author={Andreas Kleinschmidt and Matthias Nitschke and Jens Frahm},
  journal={European Journal of Neuroscience},
  year={1997},
  volume={9}
}
Fine‐scale somatotopic encoding in brain areas devoted to sensorimotor processing has recently been questioned by functional neuroimaging studies which suggested its absence within the hand area of the human primary motor cortex. We re‐examined this issue by addressing somatotopy both in terms of functional segregation and of cortical response preference using oxygenation‐sensitive magnetic resonance imaging at high spatial resolution. In a first step, spatial representations of self‐paced… 
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Functional somatotopy of finger representations in human primary motor cortex
TLDR
Functional mapping of individual movements of all fingers was performed in healthy young subjects and confirmed previous concepts that finger somatotopy in the human M1 hand area emerges as a functional predominance of individual digit representations sharing common areas in a distributed though ordered network.
Complex organization of human primary motor cortex: a high-resolution fMRI study.
TLDR
A violation of a traditional somatotopic order suggests that the motor cortex is not merely a map of the body but is topographically shaped by other influences, perhaps including correlations in the use of body parts in the motor repertoire.
Somatotopy in human primary motor and somatosensory hand representations revisited.
TLDR
High-resolution functional magnetic resonance imaging of healthy volunteers was used to study the functional anatomy of the human primary motor and somatosensory cortical hand representations during simple movements of thumb, little finger and wrist, suggesting a somatotopic arrangement exists for both M1 and S1 hand representations.
fMRI Evaluation of Somatotopic Representation in Human Primary Motor Cortex
We used fMRI to map foot, elbow, fist, thumb, index finger, and lip movements in 30 healthy subjects. For each movement type confidence intervals of representational sites in the primary motor cortex…
Finger Somatotopy in Human Motor Cortex
TLDR
Results show a highly significant though small scale somatotopy of fingerspecific activation patterns in the order indicated by Penfields motor homunculus and considerable overlap of finger specific BOLD responses was found.
Somatotopic mapping of the human primary sensorimotor cortex during motor imagery and motor execution by functional magnetic resonance imaging
Novel imaging techniques to study the functional organization of the human brain
Despite more than a century of investigation into the cortical organization of motor function, the existence of motor somatotopy is still debated. We review functional magnetic resonance imaging…
Magnetoencephalography indicates finger motor somatotopy
TLDR
Besides replication of the overlap aspect, it is found statistically significant evidence for the existence of a somatotopic aspect of human hand motor representation when comparing the fifth and first finger motor dipoles along the superior–inferior axis.
Functional somatotopy revealed across multiple cortical regions using a model of complex motor task
The primary motor cortex (M1) possesses a functional somatotopic structure-representations of adjacent within-limb joints overlap to facilitate coordination while maintaining discrete centers for…
Finger representations in human primary somatosensory cortex as revealed by high-resolution functional MRI of tactile stimulation
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References

SHOWING 1-10 OF 21 REFERENCES
Somatotopic motor representation in the human anterior cerebellum. A high-resolution functional MRI study.
TLDR
The representation of hand, foot and tongue movements in the anterior cerebellar lobe of eight healthy subjects is delineated using dynamic high-resolution MRI sensitized to changes in cerebral blood oxygenation (CBO).
Somatotopic mapping of the human primary motor cortex with functional magnetic resonance imaging
TLDR
Functional magnetic resonance imaging (FMRI) was applied to map the somatotopic organization of the primary motor cortex using voluntary movements of the hand, arm, and foot to indicate that FMRI is capable of generating somatOTopic maps of thePrimary motor cortex in individual subjects.
Somatotopic mapping of the primary motor cortex in humans: activation studies with cerebral blood flow and positron emission tomography.
TLDR
The somatotopic representation of the human primary motor cortex was examined noninvasively with estimates of cerebral blood flow obtained with positron emission tomography and it was determined that two foci of activation in theprimary motor cortex could be discriminated with a 95% confidence if they were separated by 5.4 mm.
Shared neural substrates controlling hand movements in human motor cortex.
TLDR
A functional magnetic resonance imaging method that measures relative cerebral blood flow was used to identify a distributed, overlapping pattern of hand movement representation within the posterior precentral gyrus, which contains M1.
Functional cooperativity of human cortical motor areas during self-paced simple finger movements. A high-resolution MRI study.
TLDR
The present MRI findings readily demonstrate in single subjects that the SMA is involved in self-paced finger tapping, and only sparse activation in the ipsilateral primary motor cortex is consistent with the motor paradigm used.
Neurophysiological correlates of hand preference in primary motor cortex of adult squirrel monkeys
TLDR
It is suggested that a large source of variability found in the topography of motor maps in this and other studies derives from differences in the way particular movements and/or movement combinations are performed by individual animals.
How somatotopic is the motor cortex hand area?
TLDR
Electrical stimulation showed that single M1 neurons were active with movements of different fingers and a population of neurons distributed throughout the M1 hand area rather than a somatotopically segregated population.
Activation of precentral and mesial motor areas during the execution of elementary proximal and distal arm movements: a PET study.
TLDR
The results showed that proximal and distal arm movements are to a large extent segregated in the precentral motor cortex, but not in the SMA, and that the S MA is made of at least two functional sectors, only the caudal one is activated during simple aimless movements.
Two different areas within the primary motor cortex of man
TLDR
It is shown that area 4 in man can be subdivided into areas '4 anterior' and '4 posterior' (4p) on the basis of both quantitative cytoarchitecture and quantitative distributions of transmitter-binding sites and by positron emission tomography that two representations of the fingers exist.
Homuncular organization of human motor cortex as indicated by neuromagnetic recordings
TLDR
Findings indicate that neuromagnetic recordings are capable of localizing cortical activity associated with voluntarily produced movements without the use of external stimulation and provide a new method for studying the functional organization of human motor cortex and its role in voluntary movement.
...
1
2
3
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