Somatostatin receptors on thyrotropin-secreting pituitary adenomas: comparison with the inhibitory effects of octreotide upon in vivo and in vitro hormonal secretions.

Abstract

The in vivo and in vitro inhibitory effects of a somatostatin (SRIH) analog, octreotide, upon TSH, alpha-subunit, GH, and PRL have been studied, as well as SRIH receptors and their coupling to adenylate cyclase, in nine TSH-secreting pituitary adenomas. From in vivo and cell culture studies, the TSH- and alpha-subunit-secreting adenomas appeared… (More)

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@article{Bertherat1992SomatostatinRO, title={Somatostatin receptors on thyrotropin-secreting pituitary adenomas: comparison with the inhibitory effects of octreotide upon in vivo and in vitro hormonal secretions.}, author={J er{\^o}me Bertherat and Th Brue and Alain Enjalbert and Ginette Gunz and Ramahefarizo Rasolonjanahary and Andr{\'e} Warnet and P h Jaquet and Jacques Epelbaum}, journal={The Journal of clinical endocrinology and metabolism}, year={1992}, volume={75 2}, pages={540-6} }