Somatostatin receptor subtype expression in human thyroid tumours.

  title={Somatostatin receptor subtype expression in human thyroid tumours.},
  author={Antje Klagge and Kerstin B Krause and Katrin Schierle and Frank Steinert and Henning 5 Dralle and Dagmar Fuhrer},
  journal={Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme},
  volume={42 4},
Somatostatin receptors (SSTR) are expressed in various endocrine tumours. The expression of SSTR at the tumour cell surface confers the possibility for diagnostic imaging and therapy of tumours using radiolabeled somatostatin analogues. The majority of currently available somatostatin analogues show a higher binding affinity for the SSTR2 subtype. To date, the precise expression pattern of the SSTR subtypes 1-5 in thyroid epithelial tumours remains to be determined. We investigated the mRNA… CONTINUE READING
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