Somatostatin receptor subtype expression in human tumors.

@article{Hofland2001SomatostatinRS,
  title={Somatostatin receptor subtype expression in human tumors.},
  author={Leo J. Hofland and Steven W. J. Lamberts},
  journal={Annals of oncology : official journal of the European Society for Medical Oncology},
  year={2001},
  volume={12 Suppl 2},
  pages={S31-6}
}
The presence of functional SSR in tumors has several clinical implications which include the possibility a) to control hormonal hypersecretion and related symptomatology by treatment with SS-analogs, b) to detect SSR positive tumors and their metastases by in vivo SSR scintigraphy, and c) to carry out SSR-targeted radiotherapy using radiolabeled SS-analogs. The majority of SSR positive tumors show a differential expression of somatostatin receptor subtypes, sst2 receptors being the most… CONTINUE READING
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