Somatostatin receptor-mediated imaging and therapy: basic science, current knowledge, limitations and future perspectives

@article{Breeman2001SomatostatinRI,
  title={Somatostatin receptor-mediated imaging and therapy: basic science, current knowledge, limitations and future perspectives},
  author={Wout A. P. Breeman and Marion de Jong and Dik J. Kwekkeboom and Roelf Valkema and Willem H. Bakker and Peter P. M. Kooij and Theo J. Visser and Eric P. Krenning},
  journal={European Journal of Nuclear Medicine},
  year={2001},
  volume={28},
  pages={1421-1429}
}
In vivo somatostatin receptor-mediated scintigraphy has proven to be a valuable method for the visualisation of neuroendocrine tumours and their metastases. A new application is the use of radiolabelled analogues for somatostatin receptor-mediated therapy. This paper presents a review on the basic science, historical background and current knowledge of somatostatin receptor subtypes and their expression in neuroendocrine tumours. New somatostatin analogues, new chelators, "new" radionuclides… CONTINUE READING