Somatostatin is an immunosuppressive factor in aqueous humor.

  title={Somatostatin is an immunosuppressive factor in aqueous humor.},
  author={Andrew W. Taylor and David G. Yee},
  journal={Investigative ophthalmology & visual science},
  volume={44 6},
PURPOSE To detect the presence of somatostatin (SOM) in normal aqueous humor and to characterize its immunosuppressive activity. METHODS Fresh rabbit aqueous humor was assayed for SOM by competitive ELISA. Primed T cells stimulated through their T-cell receptor (TCR) were treated with SOM at concentrations that ranged the level of SOM found in normal aqueous humor. The T cells were assayed for proliferation, lymphokine production, and immunosuppressive activity. RESULTS Normal rabbit… CONTINUE READING