Somatostatin gene regulation.

@article{Andrisani1990SomatostatinGR,
  title={Somatostatin gene regulation.},
  author={Ourania M Andrisani and Jack E. Dixon},
  journal={Annual review of physiology},
  year={1990},
  volume={52},
  pages={793-806}
}
Since the cloning of the somatostatin cDNA and gene, the efforts of a number of laboratories have contributed to the understanding of somatostatin gene expression and regulation. A genetic element located approximately 40 nucleotides upstream from the somatostatin mRNA cap site is important in the expression and cAMP-induced transcription of this neuropeptide gene. The identification of this genetic element has enabled the identification, purification, and cloning of a new class of proteins… CONTINUE READING