Somatostatin gene regulation.

  title={Somatostatin gene regulation.},
  author={Ourania M Andrisani and Jack E. Dixon},
  journal={Annual review of physiology},
Since the cloning of the somatostatin cDNA and gene, the efforts of a number of laboratories have contributed to the understanding of somatostatin gene expression and regulation. A genetic element located approximately 40 nucleotides upstream from the somatostatin mRNA cap site is important in the expression and cAMP-induced transcription of this neuropeptide gene. The identification of this genetic element has enabled the identification, purification, and cloning of a new class of proteins… CONTINUE READING