Somatostatin acts through G-proteins on dopaminergic adenylate cyclase in the caudate-putamen of the rat

Abstract

Somatostatin was incubated in an adenylate cyclase assay of a particulate fraction of caudateputamen tissue of the rat in order to examine the effect of the peptide on D-1 receptor coupled adenylate cyclase in vitro. Somatostatin was able to enhance cyclic AMP formation in the presence of guanylylimidodiphosphate and guanosine-triphosphate. In contrast to… (More)
DOI: 10.1007/BF01101708

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