Somatostatin Interneurons Control a Key Component of Mismatch Negativity in Mouse Visual Cortex.

@article{Hamm2016SomatostatinIC,
  title={Somatostatin Interneurons Control a Key Component of Mismatch Negativity in Mouse Visual Cortex.},
  author={Jordan P. Hamm and Rafael Yuste},
  journal={Cell reports},
  year={2016},
  volume={16 3},
  pages={
          597-604
        }
}
Patients with schizophrenia have deficient sensory processing, undermining how they perceive and relate to a changing environment. This impairment can be captured by the reduced mismatch negativity (MMN) index, an electroencephalographic biomarker of psychosis. The biological factors contributing to MMN are unclear, though mouse research, in which genetic and optical methods could be applied, has given some insight. Using fast two-photon calcium imaging and multielectrode recordings in awake… CONTINUE READING
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