Somatosensory afferent inputs release 5-HT and NA from the spinal cord

@article{Men1996SomatosensoryAI,
  title={Somatosensory afferent inputs release 5-HT and NA from the spinal cord},
  author={Disheng Men and Aiko Matsui and Yoichiro Matsui},
  journal={Neurochemical Research},
  year={1996},
  volume={21},
  pages={1515-1519}
}
Endogenous serotonin (5-HT) and noradrenaline (NA) release by somatosensory afferent inputs was investigated at the level of the spinal cord using in vivo microdialysis technique combined with high performance liquid chromatography and electrochemical detection (HPLC-ECD). Selective stimulation of large myelinated Aβ afferent fibers significantly increased 5-HT release to 151.1 ±10.1% of the control, but did not affect NA release. However, selective stimulation of small myelinated Aδ fibers… CONTINUE READING

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