Somatomedin-C/insulinlike growth factor I (Sm-C/IGF-I) and insulinlike growth factor II (IGF-II) mRNAs during lung development in the rat.


Somatomedins/insulinlike growth factors (Sm/IGFs) are peptide growth factors that are synthesized in multiple tissues and have been implicated in organ growth. Poly(A +)RNAs from lungs of fetal and postnatal rats were examined by dot and Northern blot analyses to investigate the local synthesis of IGFs during lung organogenesis. Blots were successively… (More)


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