Somatic sex-determining signals act on XX germ cells in Drosophila embryos.

  title={Somatic sex-determining signals act on XX germ cells in Drosophila embryos.},
  author={Susanne Staab and Anette Heller and Monica Steinmann-Zwicky},
  volume={122 12},
In Drosophila, the enhancer-trap line mgm1 is already specifically expressed in male germ cells. Staining is first detected in 10-hour-old embryos and it is found in later stem cells. This line, which reveals the earliest sex-specific gene expression in the germline known so far, is a useful molecular marker to assess the sexual pathway that germ cells have entered before any overt sexual dimorphism is apparent. XY germ cells that develop in feminized animals express mgm1, which shows that this… CONTINUE READING
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