Somatic cell reprogramming for regenerative medicine: SCNT vs. iPS cells

  title={Somatic cell reprogramming for regenerative medicine: SCNT vs. iPS cells},
  author={Guangjin Pan and Tao Wang and Hongjie Yao and Duanqing Pei},
Reprogramming of somatic cells to a pluripotent state holds huge potentials for regenerative medicine. However, a debate over which method is better, somatic cell nuclear transfer (SCNT) or induced pluripotent stem (iPS) cells, still persists. Both approaches have the potential to generate patient‐specific pluripotent stem cells for replacement therapy. Yet, although SCNT has been successfully applied in various vertebrates, no human pluripotent stem cells have been generated by SCNT due to… 

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