Somatic cAMP signaling regulates MSP-dependent oocyte growth and meiotic maturation in C. elegans.

@article{Govindan2009SomaticCS,
  title={Somatic cAMP signaling regulates MSP-dependent oocyte growth and meiotic maturation in C. elegans.},
  author={J. Amaranath Govindan and Saravanapriah Nadarajan and Seongseop Kim and Todd A Starich and David Greenstein},
  journal={Development},
  year={2009},
  volume={136 13},
  pages={2211-21}
}
Soma-germline interactions control fertility at many levels, including stem cell proliferation, meiosis and gametogenesis, yet the nature of these fundamental signaling mechanisms and their potential evolutionary conservation are incompletely understood. In C. elegans, a sperm-sensing mechanism regulates oocyte meiotic maturation and ovulation, tightly coordinating sperm availability and fertilization. Sperm release the major sperm protein (MSP) signal to trigger meiotic resumption (meiotic… CONTINUE READING

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