Somatic Cell Reprogramming into Cardiovascular Lineages.

  title={Somatic Cell Reprogramming into Cardiovascular Lineages.},
  author={Jenny Chen and Karolina A Plonowska and Sean M Wu},
  journal={Journal of cardiovascular pharmacology and therapeutics},
  volume={19 4},
Ischemic cardiac disease is the leading cause of death in the developed world. The inability of the adult mammalian heart to adequately repair itself has motivated stem cell researchers to explore various strategies to regenerate cardiomyocytes after myocardial infarction. Over the past century, progressive gains in our knowledge about the cellular mechanisms governing fate determination have led to recent advances in cellular reprogramming. The identification of specific factors capable of… CONTINUE READING